There are substantial limitations in our understanding of the distribution of antibiotic resistance in humans and livestock in developing countries. A new article published in the International Journal of Antimicrobial Agents presents the results of an epidemiological study examining patterns of antimicrobial resistance in Escherichia coli isolates circulating in sympatric human and livestock samples from 99 households across Nairobi, Kenya. The E. coli isolates were tested for susceptibility to 13 antimicrobial drugs representing nine antibiotic classes.